Apr 1986 Joined the Company Apr 2005 General Manager, Urology Project Promotion Group, Development Division, the Company Jun 2010 Executive Officer, the Company; concurrently Global TA Head (Urology), Astellas Pharma Europe B.V. Oct 2010 Executive Officer, Assistant to Head of Development Division, the Company; concurrently Global TA Head (Urology), Astellas Pharma Global Development, Inc. Apr 2011 Executive Officer, General Manager, Product Strategy Department, the Company Apr 2012 Executive Officer, in charge of Corporate Strategy, the Company Jun 2012 Senior Executive Officer, in charge of Corporate Strategy, the Company Apr 2017 Senior Executive Officer, in charge of Corporate Strategy and Sales, the Company Jun 2017 Representative Director, Executive Vice President, in charge of Corporate Strategy and Sales, the Company Apr 2018 Representative Director, President, the Company Apr 2023 Representative Director, Chairman, the Company (current) Mar 2024 Outside Director, Resonac Holdings Corporation (current)

Apr 1986 Joined the Company Oct 2010 President & CEO, OSI Pharmaceuticals, Inc. Apr 2012 Senior Vice President, Chief Strategy Officer, Astellas Pharma Europe Ltd. Jul 2014 General Manager, Licensing & Alliance Department, the Company Jun 2016 Executive Officer, General Manager, Corporate Planning Department, the Company Apr 2018 Executive Officer, in charge of Corporate Strategy, the Company Jun 2019 Representative Director, Executive Vice President, in charge of Corporate Strategy, the Company Oct 2019 Representative Director, Executive Vice President, in charge of Corporate Strategy and Finance, the Company Sep 2021 Representative Director, Executive Vice President, in charge of Corporate Strategy and Finance; concurrently in charge of Strategy Implementation, the Company Apr 2022 Representative Director, Executive Vice President, in charge of Corporate Strategy, the Company Apr 2023 Representative Director, President, the Company (current)

Apr 1991 Joined Asahi Kasei Corporation Jan 2005 Director, Human Resources, Medical Device Division, Johnson & Johnson K.K. Nov 2008 General Manager, Human Resources, Hilti (Japan) Ltd. Aug 2012 Executive Officer, General Manager, Human Resources and General Affairs, AstraZeneca K.K. Jul 2016 Executive Officer, Senior Managing Director, General Manager, Human Resources, Microsoft Japan Co., Ltd. May 2021 Head of Human Resources Division, the Company (now Head of Human Resources) (current) Oct 2022 Managing Executive Officer, in charge of Human Resources and Compliance, the Company Jun 2023 Representative Director, Executive Vice President, in charge of Human Resources and Compliance, the Company Apr 2025 Representative Director, Executive Vice President, in charge of Human Resources, the Company (current)

Apr 1977 Joined Nissei Sangyo Co., Ltd. (now Hitachi High-Tech Corporation) Mar 1990 Chief Representative, Kuala Lumpur Representative Office, Nissei Sangyo (Singapore) Pte. Ltd. (now Hitachi High-Tech (Singapore) Pte. Ltd.) Jan 1995 General Manager, Electronic Components Division, Nissei Sangyo America, Ltd. (now Hitachi High-Tech America, Inc.) Jul 2004 General Manager, Electronics Sales Division, Hitachi High-Technologies Corporation (now Hitachi High-Tech Corporation) Apr 2007 Executive Officer, General Manager, Western Japan Branch and Kansai Branch, Hitachi High-Technologies Corporation Apr 2010 President and CEO, Hitachi High-Technologies America, Inc. (now Hitachi High-Tech America, Inc.) Jun 2015 Representative Executive Officer, President and Director, Hitachi High-Technologies Corporation (now Hitachi High-Tech Corporation) Apr 2021 Senior Advisor, Hitachi High-Tech Corporation Jun 2022 Outside Director, Kurita Water Industries Ltd. (current) Jun 2023 Director, the Company (current)

Apr 1991 Joined the Company Apr 2015 General Manager, Bioscience Research Institute, Research Division, the Company Apr 2017 General Manager, Research Control Department, Research Division, the Company Apr 2022 General Manager, Research Management and Control Department, Development Research, the Company Jan 2023 Special Advisor, Audit and Supervisory Committee Office, the Company Apr 2023 General Manager, Audit and Supervisory Committee Office, the Company Jun 2024 Director (Full-time Audit and Supervisory Committee Member), the Company (current)

May 1993 Assistant, Department of Internal Medicine, Keio University School of Medicine Apr 1995 Deputy Chief, Department of Internal Medicine, Tokyo Electric Power Company Hospital Apr 2002 Director, Midori-cho Clinic Center; concurrently Director, Midori-cho Internal Medicine Clinic Jul 2005 Chief Physician, Division of Nephrology, Endocrinology and Metabolism, Department of Internal Medicine, Saitama City Hospital Apr 2007 Lecturer, Department of Nephrology, Saitama Medical University Aug 2007 Lecturer, Center for Community Medicine, Saitama Medical University Apr 2013 Associate Professor, Center for Community Medicine; concurrently Associate Professor, Department of Nephrology, Saitama Medical University Apr 2020 Visiting Professor, Department of Social Medicine, Research Administration Center and Medical Education Center, Saitama Medical University (current) Jun 2023 Director, the Company (current)

Sep 1990 Associate, Palmer & Dodge LLP (now Locke Lord LLP) Feb 1996 Corporate Counsel, Genzyme Corporation Nov 1999 Vice President, Oncology Business Development, Genzyme Corporation Jun 2003 Senior Vice President and General Manager, Oncology, Genzyme Corporation Jul 2008 President, Transplant, Oncology and Multiple Sclerosis, Genzyme Corporation Sep 2011 Chief Executive Officer and Director, Proteostasis Therapeutics, Inc. (now Kineta, Inc.) Jul 2012 Outside Director, Fate Therapeutics, Inc. Aug 2013 Head of Business Unit, Internal Medicine, Shire plc May 2014 Head of Corporate Development, Shire plc May 2016 President, Chief Executive Officer and Director, ImmunoGen Inc. (now AbbVie Inc.) Sep 2017 Outside Director, Keryx Biopharmaceuticals, Inc. (now Akebia Therapeutics, Inc.) Mar 2020 Outside Director, LogicBio Therapeutics, Inc. (now Alexion Pharmaceuticals, Inc.) May 2021 Outside Director, Ergomed plc (now Ergomed Group Limited) Dec 2023 Outside Director, BioMarin Pharmaceutical Inc. (current) May 2024 Outside Director, Ergomed Group Limited (current) May 2025 Outside Director, Charles River Laboratories International, Inc. (current) Jun 2025 Director, the Company (current)

Apr 1992 Joined Sanwa Bank, Ltd. (now MUFG Bank, Ltd.) (Left Jul 1994) Apr 1999 Registered as attorney-at-law (Tokyo Bar Association) Apr 1999 Joined Baba Law Office (now Baba & Sawada Law Office) (current) Jun 2019 Outside Director, Goldwin, Inc. (current) Jun 2023 Director (Audit and Supervisory Committee Member), the Company (current)

Oct 1991 Joined Century Audit Corporation (now EY ShinNihon LLC) (Left Oct 2001) Mar 1995 Registered as Certified Public Accountant Feb 2006 Principal, Aramaki CPA Office (current) Apr 2006 Registered as Certified Tax Accountant Jun 2008 Outside Audit & Supervisory Board Member, Sanki Holdings Co., Ltd. (now Paris Miki Holdings Inc.) Jun 2015 Director in charge of IR, Paris Miki Holdings Inc. Dec 2015 Outside Audit & Supervisory Board Member, Sacos Co., Ltd. Jun 2018 Outside Audit & Supervisory Board Member, Kyowa Exeo Corporation (now EXEO Group, Inc.) Mar 2022 Outside Director, Fuji Soft Inc. Jun 2023 Outside Director, EXEO Group, Inc. (current) Jun 2023 Outside Director (Audit and Supervisory Committee Member), TRE Holdings Corporation (current) Jun 2024 Director (Audit and Supervisory Committee Member), the Company (current)

Apr 1981 Joined NEC Corporation Jul 1998 Managing Manager, Finance Department, NEC Corporation Mar 2005 General Manager, Sales Accounting Department, Pfizer Japan Inc. Dec 2006 Executive Officer, Head of Corporate Planning Office, SS Pharmaceutical Co., Ltd. Jun 2007 Executive Officer, Chief Financial Officer, MISUMI Group Inc. Jan 2009 Director, Head of Accounting & Finance, Wyeth K.K. (now Pfizer Japan Inc.) Feb 2011 Director, Executive Officer, Head of Accounting & Finance, Chief Financial Officer, Pfizer Japan Inc. (Left Feb 2020) Apr 2020 Managing Executive Officer, Head of Corporate Management Promotion, Kansai Paint Co., Ltd. Jun 2021 Director, Senior Managing Executive Officer, Head of Corporate Management Promotion Division, Kansai Paint Co., Ltd. Apr 2022 Representative Director, Vice President Executive Officer, Head of Corporate Management Promotion Division, Kansai Paint Co., Ltd. Apr 2024 Representative Director, Vice President Executive Officer, Chief Financial Officer, Kansai Paint Co., Ltd. Jul 2025 Advisor, Kansai Paint Co., Ltd. (current) Jun 2026 Director (Audit and Supervisory Committee Member), the Company (current)