Apr 1981 Joined UBSJ Co., Ltd. (formerly Shimada Kikai Co., Ltd.) Sep 1991 Representative Director, UBSJ Co., Ltd. Apr 2007 Director, Labo Recycle Co., Ltd. (current) Apr 2009 Director, Science Hub Services PTE Ltd., Singapore (current) Dec 2019 Representative Director, Cancer Precision Medicine, Inc. (current) Dec 2021 Chairman of the Board and Director, UBSJ Co., Ltd. (current) Dec 2021 Head of Corporate Planning Office, the Company Jun 2022 Director, the Company Jul 2022 Representative Director, President, the Company (current) Jul 2022 Representative Director, President, Imnas Pharma Co., Ltd.

Apr 1966 Joined Fukui Bank, Ltd. Oct 1974 Founded Wilbee Co., Ltd. Apr 1977 Representative Director, Wilbee Co., Ltd. (current) Jun 2020 Director, Chairman of the Board, the Company (current)

Apr 2008 Researcher, Center for Genomic Medicine, RIKEN (formerly Institute of Physical and Chemical Research) Nov 2010 Postdoctoral Researcher, Cancer Center, Cold Spring Harbor Laboratory, USA Apr 2013 Associate Professor, University of Chicago Pritzker School of Medicine, USA Jul 2017 Joined the Company as Chief Scientific Officer (current) Jul 2017 Director, Cancer Precision Medicine, Inc. (current) Nov 2017 Director of Clinical Laboratory, Cancer Precision Medicine, Inc. Jun 2018 Director, the Company (current) Feb 2019 Head of R&D Department, Cancer Precision Medicine, Inc. Dec 2019 Representative Director, President, the Company Dec 2019 Representative Director, President, Imnas Pharma Co., Ltd. Dec 2023 Director in charge of Administration Division, the Company (current) Oct 2025 Director, Japan Branch Manager, IMBdx, Inc. (current)

Jun 1982 Clinical Resident, Second Department of Surgery, Hyogo College of Medicine Sep 1989 Specially Appointed Researcher, Biochemistry Division, Cancer Institute, Japanese Foundation for Cancer Research Sep 1991 Research Fellow, Department of Medical Informatics, University of Utah Medical Center, USA Mar 1995 Researcher, Biochemistry Division, Cancer Institute, Japanese Foundation for Cancer Research Oct 1995 Chief Researcher, Genome Analysis Research Department, Cancer Chemotherapy Center, Japanese Foundation for Cancer Research Apr 1997 Head, Genetic Diagnosis Research Department, Cancer Institute, Japanese Foundation for Cancer Research Apr 2002 Contract Head, Genetic Diagnosis Research Department, Cancer Institute, Japanese Foundation for Cancer Research Apr 2002 Professor, Molecular Genetics, Division of Genome Applied Medicine, Medical Research Institute, Tokyo Medical and Dental University Apr 2002 Professor, Genetic Applied Medicine, Advanced Medical Development Course, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University Apr 2022 Professor Emeritus, Tokyo Medical and Dental University (current) Apr 2022 Visiting Professor, Precision Medicine Development Research Center, University of Tsukuba (current) Jun 2022 Director, the Company (current) Mar 2023 Director, Imnas Pharma Co., Ltd. Mar 2023 Director, Cancer Precision Medicine, Inc. (current) Apr 2023 Full-time Advisor, Genomic Medicine, Medical Corporation Iseikai Oct 2023 Specially Appointed Vice Director, Iseikai International General Hospital (current)

Oct 1995 Joined Chuo Audit Corporation Apr 1998 Registered as Certified Public Accountant Jul 2000 Opened Yuichi Komine CPA Office Oct 2000 Registered as Certified Tax Accountant Oct 2000 Opened Yuichi Komine Tax Accountant Office Jan 2008 Established Sogo Tax & Accounting Corporation (formerly Komine Accounting Office Tax Corporation) Jun 2008 Corporate Auditor, the Company Jun 2010 Corporate Auditor, Ikuyo Co., Ltd. Jul 2011 Partner, Sogo Tax & Accounting Corporation Jun 2012 Corporate Auditor, Sun Life Co., Ltd. Jun 2012 Corporate Auditor, Institute of Medical Biology Co., Ltd. Sep 2014 Director, the Company (current) Mar 2016 Representative Partner, Sogo Tax & Accounting Corporation (current) Feb 2017 Director, Imnas Pharma Co., Ltd. Oct 2018 Director (Audit and Supervisory Committee Member), Sun Life Holdings Co., Ltd. (current)

Oct 1995 Joined Cancer Chemotherapy Center, Japanese Foundation for Cancer Research Mar 2000 Polymorphism Information Database Development Project, Japan Science and Technology Agency Apr 2002 Joined the Company, Drug Discovery Research Laboratory, Research Division Aug 2012 Research Department, Research and Development Division, the Company Sep 2014 Tumor Immunology Analysis Department, the Company Nov 2017 Seconded to Cancer Precision Medicine, Inc., Tumor Immunology Analysis Department Dec 2017 Seconded to Cancer Precision Medicine, Inc., R&D Department Jun 2020 Seconded to Cancer Precision Medicine, Inc., Testing Department Jun 2021 Corporate Auditor, the Company (current) Jun 2021 Corporate Auditor, Imnas Pharma Co., Ltd. Jun 2021 Corporate Auditor, Cancer Precision Medicine, Inc. (current)

Apr 2000 Professor, Nihon University Research Institute for Integrated Science Jun 2004 Corporate Auditor, the Company (current) Oct 2006 Member, Bioethics Expert Committee, Council for Science and Technology Policy, Cabinet Office, Japan Apr 2008 Program Director, New Energy and Industrial Technology Development Organization (NEDO) Apr 2017 Senior Research Fellow, Japan Education Foundation Apr 2018 Professor, Faculty of Human Welfare, Tokyo Tsushin University Apr 2023 Specially Appointed Professor, Tokyo Tsushin University (current)

Oct 1995 Joined Chuo Audit Corporation Jun 2000 Registered as Certified Public Accountant Feb 2010 Opened Tajima Certified Public Accountant Office, Representative (current) Jul 2010 Registered as Certified Tax Accountant Sep 2014 Corporate Auditor, PRISM BioLab Co., Ltd. (current) Sep 2014 Supervisory Officer, Tosei REIT Investment Corporation (current) Sep 2014 Corporate Auditor, the Company (current) Dec 2015 Representative Director, Tajima Accounting Office Co., Ltd. (current) Mar 2016 Corporate Auditor, RenaCell Therapeutics Co., Ltd. (current) Aug 2018 Director (Audit and Supervisory Committee Member), Modalis Therapeutics Corporation (current) Feb 2021 Corporate Auditor, J-Pharma Co., Ltd. Jun 2023 Corporate Auditor, Matsuya Foods Holdings Co., Ltd. (current) Sep 2023 Director (Audit and Supervisory Committee Member), J-Pharma Co., Ltd. (current)