Apr 1986 Joined Nomura Securities Co., Ltd. Jan 2008 Representative Director, Quiet Partners Co., Ltd. Sep 2010 Representative Director, With Partners Co., Ltd. Mar 2012 Director, the Company Mar 2017 Director, ALBERT Co., Ltd. May 2020 Chairman and Director, ALBERT Co., Ltd. May 2020 Representative Director, President and CEO, With Partners Co., Ltd. Jun 2021 Director, the Company Jan 2023 Chairman and Director, the Company Jun 2025 Representative Director, Chairman, the Company Dec 2025 Representative Director, Chairman and President, CEO, the Company (current) Dec 2025 Director, Nano Bridge Investment Co., Ltd. (current)

Apr 1989 Joined Hitachi, Ltd. Mar 2000 Joined CSK Venture Capital Co., Ltd. Feb 2004 Director, CSK Venture Capital Co., Ltd. Sep 2010 Executive Officer, With Partners Co., Ltd. Mar 2012 Director, the Company Mar 2015 Managing Director, Fund Business CIO, With Partners Co., Ltd. Mar 2017 Director, ALBERT Co., Ltd. Jun 2021 Director, the Company Jun 2021 Director, COO and Co-CIO, With Partners Co., Ltd. Apr 2024 Representative Director, President, With Partners Co., Ltd. Jul 2025 Senior Advisor, the Company Dec 2025 Director, CIO, the Company (current) Dec 2025 Representative Director, President, Nano Bridge Investment Co., Ltd. (current)

Apr 1989 Joined Nitto Denko Corporation Jun 2015 Executive Officer, General Manager, Information & Functional Materials Business Division, Nitto Denko Corporation Apr 2017 Executive Officer, Head of Information & Functional Materials Business Division, Nitto Denko Corporation Jun 2017 Director, Senior Executive Officer, Head of Information & Functional Materials Business Division, Nitto Denko Corporation Jun 2019 Director, Managing Executive Officer, Nitto Denko Corporation Jun 2021 Director, Senior Managing Executive Officer, Nitto Denko Corporation Jun 2022 Representative Director, Senior Managing Executive Officer, Nitto Denko Corporation Jun 2024 Representative Director, President and CEO, Accelead Co., Ltd. Jul 2025 Senior Advisor, the Company Dec 2025 Director, CGO, the Company (current) Apr 2026 Director, NANO MRNA Co., Ltd. (current)

Apr 1984 Joined Yamazen Corporation Apr 1998 General Manager, Corporate Planning Division, Autobacs Seven Co., Ltd. Jun 2002 Executive Officer, in charge of Corporate Planning, Accounting & Finance, Public Relations and IR; General Manager, Corporate Planning Office, Autobacs Seven Co., Ltd. Jun 2004 Officer, in charge of Business Strategy Promotion; General Manager, Corporate Planning Office, Autobacs Seven Co., Ltd. Apr 2006 Director, CSO, Overall Business Strategy Promotion, Autobacs Seven Co., Ltd. May 2007 Director, CSO, Overall Business Strategy Promotion, and Co-COO, Overall Overseas Business Strategy Promotion, Autobacs Seven Co., Ltd. Apr 2010 Representative Director, President, Taiyo Co., Ltd. Apr 2013 Representative Director, President, Autobacs Nankai Co., Ltd. Apr 2014 Representative Director, President, Autobacs Fukuoka Co., Ltd. Apr 2021 Adviser, Autobacs Minami-Nihon Hanbai Co., Ltd. Jun 2023 Corporate Auditor, the Company Aug 2023 Representative Director, Value Creates Co., Ltd. (current) Jun 2025 Director, the Company Dec 2025 Chief Administrative Officer (CAO), the Company Apr 2026 Director, CFO, CAO and CCO, the Company (current)

Apr 1981 Joined Kyowa Hakko Kogyo Co., Ltd. (now Kyowa Kirin Co., Ltd.) Apr 1994 Senior Researcher, Pharmaceutical Research Laboratories, Kyowa Hakko Kogyo Co., Ltd. Apr 2001 Manager, Oncology Field, Drug Discovery Research Division, Kyowa Hakko Kogyo Co., Ltd. Apr 2006 General Manager, International Development Department and Clinical Development Department I, R&D Division, Kyowa Hakko Kogyo Co., Ltd. (successively) Oct 2008 General Manager, Clinical Development Department I, R&D Division, Kyowa Hakko Kirin Co., Ltd. (now Kyowa Kirin Co., Ltd.) Mar 2011 Executive Officer, Head of International Development, Kyowa Hakko Kirin Co., Ltd. Mar 2013 Fellow, Kyowa Hakko Kirin Co., Ltd. Mar 2017 Director, CSO, Acucela K.K. Nov 2018 Representative Director, President, Acucela K.K. Jun 2020 Director, the Company Sep 2020 Director, Head of R&D Division, CSO, the Company Sep 2022 Representative Director, President, PrimRNA Co., Ltd. Jan 2023 Representative Director, President and CEO, Head of R&D Division, CSO, the Company Oct 2023 Representative Director, President and CEO, the Company Dec 2025 Representative Director, CTO, the Company Apr 2026 Director, CTO, the Company (current) Apr 2026 Representative Director, President, NANO MRNA Co., Ltd. (current)

Apr 1978 Joined Hisamitsu Pharmaceutical Co., Inc. Jan 1991 Vice President, Business Development, TheraTech Inc. (U.S.) Oct 1993 Concurrently Representative Director, President, Nihon Ceratech Co., Ltd. Jun 1996 Representative Director, President and CEO, the Company Aug 2008 Outside Director, iPS Academia Japan, Inc. Oct 2013 Outside Director, OP NanoPharma Co., Ltd. (Taiwan) (current) Jul 2014 Outside Director, iPS Portal Inc. May 2020 Representative Director, Avida Science Co., Ltd. (current) May 2020 Adviser, Oji Pharma Co., Ltd. (current) Apr 2021 Adviser, Tokyo University of Science (current) May 2025 Special Adviser, the Company Dec 2025 Director, CNO, the Company (current)

Apr 1982 Joined Nomura Securities Co., Ltd. Apr 2003 General Manager, Corporate Finance Department I, Osaka Financial Department I (successively), Nomura Securities Co., Ltd. Oct 2007 Seconded to Nomura Asset Management Co., Ltd. Dec 2010 Seconded to LIC Nomura Mutual Fund Asset Management Pvt. Ltd. (India) Mar 2016 Managing Executive Officer, in charge of RM Division, General Manager, RM Division, Marketing Division, Hong Kong Office (successively), Rating and Investment Information, Inc. Apr 2017 Managing Executive Officer, in charge of RM Division, Sales Division and Hong Kong Office, Rating and Investment Information, Inc. Mar 2019 Senior Managing Executive Officer, in charge of Sales, Marketing and Hong Kong Office, Rating and Investment Information, Inc. Mar 2021 Director, Senior Managing Executive Officer, in charge of Sales, Marketing and Hong Kong Office, Rating and Investment Information, Inc. Mar 2024 Representative Director, President, P-ALM Capital Co., Ltd. (current) Jun 2024 Director, the Company (current)

Apr 1969 Registered as Attorney-at-Law Nov 1977 Partner, Masuda Ejiri Law Office (now Nishimura & Asahi Law Office) Sep 1986 Vice Chairman, International Exchange Committee, Japan Federation of Bar Associations Nov 1998 Corporate Auditor, Yusen Broadband Networks Co., Ltd. (now USEN Corporation) Jun 2003 Corporate Auditor, Aozora Bank, Ltd. Jun 2004 Corporate Auditor, Ando Corporation Jun 2006 Corporate Auditor, Kagome Co., Ltd. May 2010 Corporate Auditor, Mitsubishi UFJ Securities Holdings Co., Ltd. May 2010 Corporate Auditor, Mitsubishi UFJ Morgan Stanley Securities Co., Ltd. May 2010 Outside Corporate Auditor, Dip Corporation Aug 2010 Partner, Nishimura & Asahi Law Office Mar 2017 Outside Director, ALBERT Co., Ltd. Jun 2017 Outside Director, Obic Co., Ltd. (current) Aug 2017 Senior Partner, ITN Law Office (current) Dec 2025 Of Counsel, EST Partners Law Office (current) Dec 2025 Director, the Company (current)

Apr 1986 Joined Nomura Securities Co., Ltd. Jul 2008 General Manager, Real Estate Investment Business Department, Nomura Securities Co., Ltd. Apr 2013 General Manager, Overseas Sales Department, Nomura Real Estate Investment Advisors Co., Ltd. Oct 2014 Director, Executive Officer, Nomura Real Estate Investment Advisors Co., Ltd. Apr 2015 Director, Managing Executive Officer, Nomura Real Estate Investment Advisors Co., Ltd. Apr 2017 Corporate Auditor, Nomura Real Estate Investment Advisors Co., Ltd. Jun 2023 Full-time Corporate Auditor, the Company (current) Jun 2023 Managing Director, With Partners Co., Ltd.

Apr 1983 Joined Kyowa Hakko Kogyo Co., Ltd. (now Kyowa Kirin Co., Ltd.) Apr 2006 General Manager, Biochemical Planning and Administration Department, Kyowa Hakko Kogyo Co., Ltd. Jul 2007 Executive Officer, General Manager, Corporate Planning Department, Daiichi Fine Chemical Co., Ltd. Apr 2010 General Manager, Accounting Department, Kyowa Hakko Kirin Co., Ltd. (now Kyowa Kirin Co., Ltd.) Apr 2012 Executive Officer, General Manager, Corporate Planning Department, Kyowa Hakko Kirin Co., Ltd. Apr 2015 Executive Officer, General Manager, General Affairs Department, Kyowa Hakko Kirin Co., Ltd. Mar 2021 Outside Corporate Auditor, Kaiomu Bioscience Inc. Nov 2021 General Manager, Administration Department, Kyulux, Inc. (current) Mar 2025 Outside Director (Audit and Supervisory Committee Member), Kaiomu Bioscience Inc. (current) Jun 2025 Corporate Auditor, the Company (current)

Oct 2002 Registered as Attorney-at-Law; joined Asahi Komano Law Office (now Nishimura & Asahi Law Office) Apr 2007 Partner Attorney, Iota Law Office Partnership (now Iota Law Office) Apr 2012 Part-time Lecturer, Faculty of Law, Keio University (current) Sep 2012 Corporate Auditor, ABEJA, Inc. (current) Oct 2014 Outside Corporate Auditor, CRE Inc. Oct 2015 Outside Director (Audit and Supervisory Committee Member), CRE Inc. (current) Oct 2017 Representative Partner Attorney, Iota Law Office (current) Mar 2018 Supervisory Executive Director, Kashima Private REIT Investment Corporation (current) Mar 2019 Outside Corporate Auditor, CBcloud Inc. (current) Apr 2022 Outside Corporate Auditor, DUAL Holdings Co., Ltd. Mar 2024 Outside Director, DUAL Holdings Co., Ltd. (current) Jun 2025 Corporate Auditor, the Company (current)