Apr 1968 Joined Otsuka Pharmaceutical Co., Ltd. Jul 1970 Joined Kokusai Shiyaku Co., Ltd. (now Sysmex International Reagents Co., Ltd.) Nov 1977 Founded the Company; Representative Director, President Mar 2016 Representative Director, Chairman and President of the Company (current)

Apr 1983 Joined Toho Rayon Co., Ltd. (now Teijin Limited) Nov 1986 Joined the Company Apr 2008 General Manager, Intellectual Property Department Apr 2010 Executive Officer, General Manager, Intellectual Property Department Mar 2011 Director; General Manager, Intellectual Property Department; in charge of Manufacturing Department, Quality Assurance Department and Safety Management Office (current)

Apr 1986 Joined the Company May 2004 General Manager, Development Department Apr 2008 Executive Officer, General Manager, Development Department Mar 2013 Director, General Manager, Development Department Mar 2025 Director; General Manager, Development Department; in charge of Development Planning Department (current)

Apr 1986 Joined Kato Spring Manufacturing Co., Ltd. (now Advanex Inc.) Oct 1994 Joined the Company Apr 2010 Deputy General Manager, East Japan Sales Department May 2013 General Manager, East Japan Sales Department Mar 2015 Director; General Manager, Sales Headquarters; Head, Overseas Business Division (current)

Apr 1984 Joined Fukuoka Mutual Bank, Ltd. (now The Nishi-Nippon City Bank, Ltd.) May 1993 Joined the Company Sep 2015 General Manager, General Affairs Department May 2016 Executive Officer, General Manager, General Affairs Department Mar 2025 Director; General Manager, General Affairs Department; in charge of Accounting Department (current)

Apr 1968 Joined Nishi-Nippon Mutual Bank, Ltd. (now The Nishi-Nippon City Bank, Ltd.) Jun 1995 Director of the same bank Jun 2000 Managing Director of the same bank Jun 2002 Senior Managing Director of the same bank Oct 2004 Senior Managing Director, The Nishi-Nippon City Bank, Ltd. Jun 2006 Director and Deputy President, The Nishi-Nippon City Bank, Ltd. Jun 2010 Representative Director, President, FM Fukuoka Inc. Jun 2010 Director, Japan FM Network Co., Ltd. Mar 2015 Director of the Company (current) Jun 2018 Senior Advisor, FM Fukuoka Inc. Aug 2023 Audit and Supervisory Committee Member, Nyosui Audit Corporation (current)

Apr 1980 Associate Professor, Department of Biochemistry, Oita Medical University (now Oita University Faculty of Medicine) Apr 1986 Professor and Director, Division of Cancer Chemotherapy, Institute for Tumor Research, Kagoshima University Apr 2003 Professor, Department of Molecular Oncology, Graduate School of Medical and Dental Sciences, Kagoshima University; Chair, Advanced Therapeutic Sciences Apr 2010 Professor Emeritus, Kagoshima University; Specially Appointed Professor, Department of Medical Oncology, Institute of Health Biosciences, The University of Tokushima Apr 2012 Visiting Professor, The University of Tokushima; Physician, Takeda Hospital, Keitenkai Medical Corporation Oct 2013 Physician, Kashiigaoka Rehabilitation Hospital, Ikeikai Foundation Feb 2014 Deputy Director, Kashiigaoka Rehabilitation Hospital Mar 2017 Director of the Company (current) Jun 2017 Deputy Director, Yachiyo Rehabilitation Hospital, Kyoju-no-Kai Apr 2022 Director, Department of Convalescent Rehabilitation, Fukuoka Seishukai Hospital, Seishukai Medical Corporation

Apr 1986 Joined the Company May 2015 Deputy General Manager, Sales Planning Department May 2016 General Manager, Sales Planning Department Mar 2019 Full-time Audit & Supervisory Board Member of the Company (current)

Apr 1993 Joined Tohmatsu Audit Corporation (now Deloitte Touche Tohmatsu LLC) Jul 2010 Opened Shigemi Accounting Office Mar 2011 Audit & Supervisory Board Member of the Company (current) Apr 2013 Established Shigemi Accounting Tax Corporation (now Tsuji & Shigemi Tax Corporation); Representative Partner (current) May 2019 Representative Director, President, Sunlight Consulting Co., Ltd. (current) Mar 2024 Audit & Supervisory Board Member, Pacific League Marketing Corporation (current)

Apr 1979 Joined Fukuoka Pharmaceutical Co., Ltd. (now Shoyaku Co., Ltd.) Nov 2001 Joined Kenko Club Co., Ltd. Dec 2004 Representative Director, Kenko Club Co., Ltd. (current) Apr 2005 Director, Utsunomiya Hospital operated by Shiseido-do Medical Corporation Mar 2015 Audit & Supervisory Board Member of the Company (current)