Apr 1991 Joined Sumitomo Bank, Ltd. (now Sumitomo Mitsui Banking Corporation) Oct 1996 Joined Sumitomo Capital Securities, Inc. Apr 1999 Joined Daiwa SB Capital Markets Co., Ltd. (now Daiwa Securities Co. Ltd.) Sep 2006 Joined MediciNova, Inc.; Executive Vice President and Representative, Tokyo Office Jan 2007 Established MediciNova Pharma Co., Ltd.; Representative Director, President Mar 2019 Representative Director, President and COO, the Company Aug 2020 Representative Director and President, Executive Officer, the Company Oct 2023 Representative Director, President and CEO, the Company (current)

Apr 1990 Assistant Professor, Hirosaki University, Department of Dermatology, School of Medicine Hospital Oct 1990 Postdoctoral Fellow, Thomas Jefferson University Medical College, USA Dec 1992 Assistant Professor, Hirosaki University, Department of Dermatology, School of Medicine Feb 1995 Lecturer, Hirosaki University, Department of Dermatology, School of Medicine Hospital Aug 1998 Associate Professor, Hirosaki University, Department of Dermatology, School of Medicine Apr 2002 Associate Professor, Osaka University, Graduate School of Medicine, Gene Therapy May 2003 Professor, Osaka University, Graduate School of Medicine, Gene Therapy Feb 2007 Director, the Company Oct 2009 Professor, Osaka University Endowed Chair, Regenerative Medicine, Graduate School of Medicine Oct 2022 Director and CSO, the Company (current) Oct 2023 Visiting Professor, Osaka University Graduate School of Medicine (current)

Apr 1995 Joined CSK Venture Capital Co., Ltd. Jun 2014 Joined DeNA Co., Ltd. Oct 2018 Representative Director, Sun Chef Lepra Co., Ltd. (current) Sep 2019 Director, certified NPO deleteC (current) Oct 2019 Outside Director, the Company (current) Aug 2022 Team Head, Healthcare Team, Business Division, Social Change Promotion Foundation (general incorporated foundation) Feb 2024 Director, New Business Promotion Office, Medical Services Division, NTT Precision Medicine Co., Ltd. (current)

Apr 2001 Joined Ministry of Health, Labour and Welfare, Pharmaceutical and Food Safety Bureau Apr 2003 Seconded to Fukuoka Prefectural Government, Health and Welfare Department, Pharmaceutical Affairs Division Sep 2012 Seconded to Pharmaceuticals and Medical Devices Agency, Medical Device Review Department I Jul 2014 Seconded to INCJ, Ltd. Oct 2017 Joined Kyoya Co., Ltd. Dec 2017 Director, Kyoya Co., Ltd. (current) Dec 2017 Director, Pol-Med Tech Co., Ltd. (current) Mar 2018 Director, PRDM Co., Ltd. (current) May 2020 Audit & Supervisory Board Member, Regional Fish Co., Ltd. (current) Oct 2020 Outside Director, the Company (current) Jul 2022 Representative Director, Momiji Research Institute Co., Ltd. (current) Jun 2024 Director, Gifu City Pharmaceutical Association (general incorporated association) (current)

Jun 1975 Joined Uniroyal, Inc. (USA), International Division, Area Manager Feb 1985 Joined Eli Lilly Japan K.K., Arden Export Division, Section Manager Oct 1990 Joined Eli Lilly Japan K.K., Head of Western Japan Sales, Pharmaceutical Division Sep 1993 Joined Eli Lilly Japan K.K., General Manager, Human Resources Sep 1996 Joined Eli Lilly Japan K.K., General Manager, Elanco Animal Health Division Jun 1999 Joined Eli Lilly Japan K.K., General Manager, Business Development Apr 2003 Joined Eli Lilly Japan K.K., Executive Officer, General Manager, Business Development Nov 2008 Joined Shionogi & Co., Ltd., General Manager, Overseas Business Development Oct 2017 Full-time Audit and Supervisory Board Member, the Company (current)

Oct 1983 Joined Sanwa Audit Corporation Tokyo Marunouchi Office (now Deloitte Touche Tohmatsu LLC) Jul 1997 Partner, same office Oct 2005 Head, Yokohama Office, same firm Sep 2018 Representative, Ryohiro Mizukami Certified Public Accountant Office (current) Sep 2018 Director, Liberta Co., Ltd. Mar 2019 Director, Rex Advisors Co., Ltd. (current) Oct 2019 Audit and Supervisory Board Member, the Company (current) Sep 2020 Audit and Supervisory Board Member, Kudo Construction Co., Ltd. (current) Jun 2021 Director, Kojin Bio Co., Ltd.

Apr 1978 Joined Sumitomo Bank, Ltd. (now Sumitomo Mitsui Banking Corporation) Apr 1997 General Manager, Equity Division, Sumitomo Capital Securities, Inc. Apr 2003 General Manager, Nagoya Corporate Business Division, Daiwa SMBC Securities Co., Ltd. (now Daiwa Securities Co. Ltd.) Apr 2007 General Manager, Private Banking Sales Division II, Sumitomo Mitsui Banking Corporation Mar 2014 Audit and Supervisory Board Member, Aoyama Zaisan Networks Co., Ltd. Oct 2019 Audit and Supervisory Board Member, the Company (current)