Apr 1989 Joined Recruit Co., Ltd. Apr 2001 Representative Director, Sentan Kagaku Gijutsu Enterprise Co., Ltd. Nov 2005 Limited Partner, Xseed Partners LPS May 2011 Representative Director, the Company Sep 2015 Representative Director, BioMedCore Co., Ltd. May 2018 Representative Director, President, the Company (current)

Apr 2003 Professor, Faculty of Agriculture, Tokyo University of Agriculture and Technology Apr 2004 Professor, Graduate School, Tokyo University of Agriculture and Technology Jun 2005 Director, the Company May 2011 Representative Director, President, the Company May 2018 Director, the Company Jul 2021 Chairman of the Board, Director, the Company (current) Apr 2023 Specially Appointed Professor, Tokyo University of Agriculture and Technology (current)

Apr 1993 Joined Nippon Steel Corporation (now Nippon Steel Corporation) Nov 1995 Joined Misawa Management Center Co., Ltd. Apr 2000 Joined Scientia Co., Ltd. (now One Jinji Co., Ltd.) Nov 2006 General Manager, Administration Department, Scientia Co., Ltd. Feb 2018 Joined the Company; Manager, Administration Department May 2018 Director, the Company (current)

Apr 1986 Joined Funai Yakuhin Kogyo Co., Ltd. (now Sanofi K.K.) Jan 1989 Assistant, Division of Analytical Chemistry, Faculty of Pharmaceutical Sciences, Meijo University Mar 1990 Joined Ciba-Geigy Japan Ltd. (now Novartis Pharma K.K.) Jan 1998 Head, Clinical Pharmacology Office, Clinical Development and Regulatory Affairs Department, Ciba-Geigy Japan Ltd. Dec 2000 Joined Quintiles K.K.; Director, Business Development Department, Clinical Development Business Unit; Head of Japan and Korea Apr 2001 Joined Mundipharma K.K.; Head of Development Sep 2006 Joined Sanofi-Aventis K.K. (now Sanofi K.K.); Deputy Head, Pharmaceutical Development Division Nov 2010 Executive Officer, Head of Pharmaceutical Development Division, Sanofi-Aventis K.K. Dec 2013 Executive Officer, Head of Development Promotion, Asia Pacific, Sanofi K.K. Nov 2017 Executive Officer, Head of R&D, Sanofi K.K. Apr 2019 Executive Officer, Head of R&D and concurrently Head of Development Planning and Coordination, Sanofi K.K. Nov 2024 Joined the Company; Senior Director, R&D Department May 2025 Director, the Company (current)

Apr 1987 Joined Mitsubishi Corporation Dec 1996 SUASA KRISTAL (M) Berhad Nov 1998 Vice President and Director, SUASA KRISTAL (M) Berhad Dec 2002 Director, Shin Nippon Biomedical Laboratories, Ltd. Apr 2004 Executive Officer, Shin Nippon Biomedical Laboratories, Ltd.; Registered as Certified Public Accountant (US) Jun 2004 Senior Managing Director, Shin Nippon Biomedical Laboratories, Ltd. Jul 2012 Director, WAVE Life Sciences Ltd. (current) Apr 2015 Director, SNBL PPD K.K. Jun 2016 Statutory Auditor, SNBL PPD K.K. (current) Jun 2016 Vice President and Director, Shin Nippon Biomedical Laboratories, Ltd. Jun 2017 Vice President and Representative Director, Shin Nippon Biomedical Laboratories, Ltd. Mar 2020 Director, the Company (current) Director, Satsuma Pharmaceuticals, Inc. (current) Jun 2025 Vice Chairman and Director, Shin Nippon Biomedical Laboratories, Ltd. (current)

Mar 1979 Obtained medical license Jun 1984 Assistant, Aichi Medical University Oct 1988 Senior Scientist, Systemix Inc. Apr 1993 Senior Research Associate, DNAX Research Institute Apr 1997 Independent consultant providing business development support Sep 2002 Executive Director, Science & Medicine, Clearview Projects, Inc. Nov 2005 Independent consultant providing nonclinical and clinical development strategy and business development support (current) Mar 2007 Senior Vice President, Research and Strategy, Regimmune Corporation Aug 2014 Board Member, NapaJen Pharma, Inc. Nov 2017 Board Member, Promethera Biosciences May 2021 Director, the Company (current) Jun 2022 Executive Vice President, Clinical Development, Regimmune Corporation (current) Dec 2023 Venture Partner, Mitsui & Co. Global Investment, Inc. (current)

Apr 1978 Joined Sanwa Bank, Ltd. (now MUFG Bank, Ltd.) Apr 1997 Manager, Tachikawa Branch, Sanwa Bank, Ltd. Apr 2002 Manager, Shibuya Branch and General Manager, Shibuya Corporate Sales Department, Sanwa Bank, Ltd. Apr 2004 General Manager, Muromachi Branch Office, Sanwa Bank, Ltd. Oct 2006 Managing Executive Officer and Head of Development Division, Gakusei Joho Center Co., Ltd. Jun 2008 Joined AEON Bank, Ltd.; General Manager, Business Planning Department Nov 2009 Executive Officer and General Manager, Corporate Sales Department, AEON Bank, Ltd. Apr 2014 Executive Officer and General Manager, Legal and Compliance Department, AEON Bank, Ltd. Apr 2015 Executive Officer and General Manager, Internal Audit Department, AEON Bank, Ltd. Oct 2015 Seconded to AEON Financial Service Co., Ltd.; General Manager, Overseas Business Division Nov 2015 Director, AEON Financial Service (Hong Kong) Co., Ltd. Sep 2016 Statutory Auditor, AEON REIT Management Co., Ltd. May 2017 Statutory Auditor, MaxValu Tokai Co., Ltd.; Full-time Statutory Auditor, Aeon Pet Co., Ltd. May 2021 Full-time Statutory Auditor, the Company (current)

Apr 1974 Joined Mitsubishi Kasei Corporation (now Mitsubishi Chemical Group Corporation) Aug 1979 Joined Yamanouchi Pharmaceutical Co., Ltd. (now Astellas Pharma Inc.) Aug 1997 Head, Pharmacology Research Laboratories, Yamanouchi Pharmaceutical Co., Ltd. Jun 1999 Head, International Development Department, Yamanouchi Pharmaceutical Co., Ltd. Aug 2003 Executive Director; Deputy Head, Reliability Assurance Division, Yamanouchi Pharmaceutical Co., Ltd. Apr 2004 Professor, Faculty of Pharmacy, Showa University Apr 2015 Joined the Company; Head of R&D Department May 2015 Director, the Company May 2017 Full-time Statutory Auditor, the Company May 2025 Statutory Auditor, the Company (current)

Oct 2002 Joined Chuo Aoyama Audit Corporation (now Misuzu Audit Corporation) Apr 2006 Registered as Certified Public Accountant Aug 2007 Joined Shin Nihon & Co. (now EY ShinNihon LLC) Jul 2009 Opened Kenichi Nakamura Certified Public Accountant Office (current) Sep 2010 Registered as Certified Tax Accountant May 2013 Statutory Auditor, the Company (current) Jun 2024 Statutory Auditor, Hochiki Corporation Jun 2025 Director, Audit and Supervisory Committee Member, Hochiki Corporation (current)

Oct 2001 Registered as Attorney-at-Law (Tokyo Bar Association); joined Nagashima Ohno & Tsunematsu Apr 2011 Joined Secretariat of the Securities and Exchange Surveillance Commission Feb 2013 Joined Kataoka & Partners Jan 2014 Partner, Kataoka & Partners (current) Mar 2016 Statutory Auditor, Sios Technology Corporation (now Sios Inc.) Mar 2017 Director, Audit and Supervisory Committee Member, Sios Inc. (current) May 2019 Statutory Auditor, the Company (current)