Overview
Precision Instruments

3-D Matrix,Ltd.

3-D Matrix is a medical technology company that develops, manufactures, and sells medical devices and pharmaceuticals based on self-assembling peptide (SAP) technology licensed exclusively from MIT. The company operates across three therapeutic areas: surgical (hemostatic agents, submucosal injection materials, anti-adhesion materials), tissue regeneration (wound healing, alveolar bone regeneration), and drug delivery systems (DDS) for nucleic acid medicines targeting cancer and other diseases. Its flagship product, PuraStat®, is a transparent, synthetic, biocompatible hemostatic gel that differentiates from conventional biological-derived hemostats through superior safety, ease of use, and no risk of viral contamination.

Market Cap
¥46.5B
US$296M
EV
¥45.4B
US$289M
Stock¥363▲+0.28%
US$1 = ¥156.80 (2026-10-23)
LTM EV/EBITDA
24.9
x
LTM EV/EBIT
24.9
x
LTM PER
12.6
x
LTM PBR
6.7
x
Stock vs TOPIX (1Y, base=100)vs TOPIX ▲+4.3%pt
100123
Oct 24, 25 – Oct 23, 26StockTOPIX
1Mar 23, 26Market-wide: TOPIX -3.4% decline
2Jun 12, 26Full-year FY2026/04 earnings announced
3Sep 11, 26Q1 FY2027/4 earnings: Sales +46.9% YoY, operating profit +5,388.9% YoY beat
MC → EV Bridge
46.5BUS$296MMarket Cap0.60BUS$3.83M+ Debt1.69BUS$10.8M− Cash0.01BUS$0.05M− Inv. Sec.45.4BUS$289MEV
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Performance & Balance
Revenue 5Y (¥B)
1.51US$9.60M'22/42.31US$14.8M'23/44.59US$29.3M'24/46.93US$44.2M'25/410.9US$69.4M'26/4
EBITDA 5Y (¥B)
-1.16-US$7.37M'25/41.34US$8.51M'26/4
Net Income 5Y (¥B)
-1.89-US$12.1M'22/4-2.45-US$15.6M'23/4-0.26-US$1.63M'24/4-2.50-US$16.0M'25/44.16US$26.5M'26/4
Capital Structure
92%
EquityD/E 0.09xDebt
Liquidity vs Debt 5Y (¥B)▲ Net Cash
CashInv. Sec.Debt
2.85US$18.2M3.67US$23.4M'22/41.18US$7.51M4.37US$27.9M'23/41.37US$8.75M4.17US$26.6M'24/41.59US$10.1M2.94US$18.8M'25/42.84US$18.1M0.60US$3.83M'26/4
Shareholders
Top 10 hold 11.2%
1
JPMorgan Securities Japan Co., Ltd.
2.02%
2
BNY GCM CLIENT ACCOUNT JPRD AC ISG
1.76%
3
Keiji NAGANO
1.45%
4
Rakuten Securities, Inc.
1.26%
5
Shoji MATSUMOTO
1.09%
6
Yoshimi YAMADA
0.81%
7
Nomura Securities Co., Ltd.
0.79%
8
Yoshiaki ISHII
0.68%
9
Tatsuo KOBAYASHI
0.66%
10
Masayuki TERANISHI
0.65%
Management
8 officers
Toshihiko AMANUMA
Representative Director, President
Apr 2000 Joined Bain & Company, Tokyo Office Apr 2009 Managing Consultant, Headstrong K.K. (now Genpact Consulting K.K.) Jul 2010 Manager, Sony Corporation Nov 2012 Manager, 3-D Matrix, Inc. Oct 2017 Investment Director, JBIC IG Partners K.K. Jul 2019 Executive Officer and General Manager, North America Business Division of the Company Jul 2021 Director of the Company Apr 2026 Representative Director, President of the Company (current)
1975-11-27
Keiji NAGANO
Chairman of the Board, Director
Apr 1978 Joined Exxon Chemical Japan Ltd. (now Exxon Mobil GK) Jun 1986 Joined Bain & Company, Tokyo Office Apr 1993 Partner, Bain & Company, Tokyo Office Apr 1994 Head of Bain & Company, Korea Office Apr 2000 Established New Media Japan, Inc. and assumed position of Japan Representative May 2004 Established the Company; Representative Director, Chairman of the Company Mar 2016 Chairman of the Board, Director of the Company (current)
1954-06-08
Satoshi KOBAYASHI
Director
Aug 2005 Joined Fresenius Medical Care Japan Apr 2007 Joined the Company, Business Development Department May 2014 Manager, Business Development Department of the Company Jul 2017 Executive Officer and General Manager, Business Development Department of the Company Jul 2021 Director of the Company (current)
1980-11-03
Ryuhei MOTEGI
Director
Apr 1994 Registered as attorney-at-law (Tokyo Bar Association); joined Yanagida Nomura Akai Law Office (now Yanagida & Partners) Jun 2001 Joined De Bandt, Van Hecke, Lagae & Loesche (Brussels; merged with Linklaters in 2002) Aug 2003 Joined Oe & Nishimura LPC (Tokyo Office) Jan 2022 Joined the Company as General Counsel (current) Jul 2023 Director of the Company (current)
1967-01-16
Mizuki KANNO
Director
Dec 2011 Registered as attorney-at-law (Tokyo Bar Association); joined Breakmore Law Office Sep 2014 Joined Anderson Mori & Tomotsune Nov 2016 Joined Oe & Nishimura LPC Jan 2021 Partner, Oe & Nishimura LPC (current) Jul 2025 Director of the Company (current)
1981-03-29
Tsuyoshi TAKEMOTO
Audit and Supervisory Board Member (Full-time)
Apr 1980 Joined Hitachi, Ltd. Jul 2002 Manager, New Media Japan, Inc. May 2004 Representative Director, President of the Company Sep 2007 Representative, Japan Office, Unisantis FZE Jun 2008 President and Director, News Corp Asia Pacific K.K. Feb 2010 Representative Director, President, Green Trade Co., Ltd. Feb 2012 Head of Business Development Division, JANA Solutions Inc. Mar 2019 General Manager, Sales Development Department, Nitto Shoji Co., Ltd. Jul 2024 Audit and Supervisory Board Member of the Company (current)
1956-01-13
Noriyuki OKAWARA
Audit and Supervisory Board Member
Oct 2001 Registered as attorney-at-law (Tokyo Bar Association); joined Matsuo Sogo Law Office (now Matsuo Sogo Law Office LPC) Jan 2005 Joined Oe & Nishimura LPC (Tokyo Office) Jun 2006 Co-founder and Partner Attorney, Sakurazaka Law Office (now Vasco da Gama Law & Accounting Office) Aug 2008 Co-founder and Partner Attorney, Vasco da Gama Law & Accounting Office Jul 2016 Director, Max Gakuen School Corporation (current) Jun 2018 Audit and Supervisory Board Member, Tenryu Holdings Co., Ltd. (current) Oct 2022 Founder and Representative Attorney, Toranomon 3-Chome Law Office (current) Jul 2023 Audit and Supervisory Board Member of the Company (current)
1970-06-09
Koichiro ITO
Audit and Supervisory Board Member
Apr 1997 Joined Goldman Sachs Securities Co., Ltd. Nov 2005 Joined Chuo Aoyama PricewaterhouseCoopers Tax Corporation (now PwC Tax Japan) Jul 2009 Registered as Certified Public Accountant May 2011 Opened Ito International Accounting and Tax Office; Representative (current) Jan 2012 Partner, Novel International Consulting LLP (current) Feb 2014 Audit & Supervisory Board Member, Bridge Capital Asset Management Co., Ltd. Feb 2017 Audit & Supervisory Board Member, VISITS Technologies Co., Ltd. Jun 2018 Outside Director (Audit and Supervisory Committee Member), SMS Co., Ltd. Feb 2020 Director, Act Holdings Co., Ltd. (current) Jun 2020 Outside Audit & Supervisory Board Member, Jiban Net Holdings Co., Ltd. (current) Oct 2020 Outside Audit & Supervisory Board Member, Moi Inc. (current) Jun 2022 Outside Director (Audit and Supervisory Committee Member), Ii Seikatsu Co., Ltd. (current) Aug 2022 Supervisory Director, Daiwa Office Investment Corporation (current) Jul 2024 Audit and Supervisory Board Member of the Company (current)
1972-09-26
Large Shareholding Reports
J.P. Morgan Securities plc
2026-05-20
2.05%→1.99%
SBI Securities Co., Ltd.
2026-05-12
5.04%→4.32%
SBI Securities Co., Ltd.
2026-04-21
5.04%
SBI Securities Co., Ltd.
2026-04-06
5.33%→4.99%
J.P. Morgan Securities Japan Co., Ltd.
2026-04-03
2.68%
Annual report (as of 2026-04-30): 2.02%
SBI Securities Co., Ltd.
2026-03-23
5.33%→5.03%
Heights Capital Management, Inc.
2026-03-16
8.95%→7.41%
Heights Capital Management, Inc.
2026-03-11
9.49%→8.95%
Heights Capital Management, Inc.
2026-02-09
10.10%→9.49%
SBI Securities Co., Ltd.
2026-02-05
5.96%→5.33%
Heights Capital Management, Inc.
2026-01-27
11.50%→10.10%
Heights Capital Management, Inc.
2026-01-20
12.08%→11.50%
Heights Capital Management, Inc.
2026-01-05
13.22%→12.08%
SBI Securities Co., Ltd.
2025-12-04
6.17%→5.96%
Heights Capital Management, Inc.
2025-10-21
14.31%→13.22%
SBI Securities Co., Ltd.
2025-10-07
5.31%→6.17%
Heights Capital Management, Inc.
2025-10-03
14.54%→14.31%
Heights Capital Management, Inc.
2025-09-30
15.78%→14.54%
Heights Capital Management, Inc.
2025-09-22
15.64%→15.78%
Heights Capital Management, Inc.
2025-09-19
16.79%→15.64%
Heights Capital Management, Inc.
2025-08-25
17.04%→16.79%
Heights Capital Management, Inc.
2025-08-15
18.06%→17.04%
Heights Capital Management, Inc.
2025-08-04
18.06%→18.06%
Disclosures
No disclosures
Primary Source Filings
TDnet
2026-09-10
Q1 Earnings Flash
FY ending Apr 2027
EDINET
2026-07-22
Annual Securities Report
Period: May 2025 – Apr 2026
EDINET
2026-05-20
Large Shareholding Report
EDINET
2026-05-12
Large Shareholding Report
EDINET
2026-04-21
Large Shareholding Report
EDINET
2026-04-06
Large Shareholding Report
EDINET
2026-04-03
Large Shareholding Report
EDINET
2026-03-23
Large Shareholding Report
EDINET
2026-03-16
Large Shareholding Report
TDnet
2026-03-12
Q3 Earnings Flash
FY ending Apr 2026
EDINET
2026-03-11
Large Shareholding Report
EDINET
2026-02-09
Large Shareholding Report
EDINET
2026-02-05
Large Shareholding Report
EDINET
2026-01-27
Large Shareholding Report
EDINET
2026-01-20
Large Shareholding Report
EDINET
2026-01-05
Large Shareholding Report
EDINET
2025-12-11
Semi-Annual Securities Report
Period: May 2025 – Apr 2026
EDINET
2025-12-04
Large Shareholding Report
EDINET
2025-10-21
Large Shareholding Report
EDINET
2025-10-07
Large Shareholding Report
EDINET
2025-10-03
Large Shareholding Report
EDINET
2025-09-30
Large Shareholding Report
EDINET
2025-09-22
Large Shareholding Report
EDINET
2025-09-19
Large Shareholding Report
TDnet
2025-09-11
Q1 Earnings Flash
FY ending Apr 2026
EDINET
2025-08-25
Large Shareholding Report
EDINET
2025-08-15
Large Shareholding Report
EDINET
2025-08-04
Large Shareholding Report
EDINET
2025-07-24
Annual Securities Report
Period: May 2024 – Apr 2025
EDINET
2025-06-24
Securities Registration Statement
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