Apr 1981 Research Fellow, Japan Society for the Promotion of Science Apr 1982 Joined Mitsubishi Kasei Corporation (current Mitsubishi Chemical Corporation) Jan 1995 Joined Sosei Co., Ltd. Aug 2000 Joined Takara Shuzo Co., Ltd.; Director, Dragon Genomics Inc. (current Takara Bio Inc.) May 2001 Joined the Company; General Manager, Business Development Division Aug 2001 Director of the Company Sep 2002 Representative Director, President of the Company (current) Mar 2014 President, AnGes USA Inc. (current) Jan 2020 Director, EmendoBio Inc. Sep 2023 Director, Emendo Research and Development Ltd. (current) Mar 2024 CEO, EmendoBio Inc. (current)

Apr 1985 Joined Mitsubishi Kasei Corporation (current Mitsubishi Chemical Corporation) Apr 2010 Manager, International Business Division, Tanabe Mitsubishi Pharma Corporation (current Tanabe Pharma Corporation) Apr 2013 General Manager, First Department, Pharmacology Research Institute No. 2, same company Jun 2015 Seconded to Medical Innovation Center, Graduate School of Medicine, Kyoto University, as Specially Appointed Professor, TMK Project May 2020 Joined the Company; Manager, President's Office Oct 2021 General Manager, Corporate Planning Department of the Company Mar 2022 Director, General Manager, Corporate Planning Department of the Company Sep 2022 Director, EmendoBio Inc. (current) Jun 2023 Outside Director, MyBiotics Pharma Ltd. (current) Sep 2023 Director, Emendo Research and Development Ltd. Mar 2024 CEO, Emendo Research and Development Ltd. (current) Aug 2024 Director; General Manager, Corporate Planning, Finance and General Affairs Departments of the Company Nov 2025 Director, General Manager, General Affairs Department of the Company (current)

Aug 1979 Joined Ciba-Geigy Japan Limited Jan 1994 Joined Bayer Yakuhin, Ltd. Mar 1997 Director (Plant Manager, Shiga Plant), Bayer Yakuhin, Ltd. Jul 2002 Representative Director, President, Bayer Yakuhin, Ltd. Jan 2007 Representative Director, Chairman, Bayer Yakuhin, Ltd. Apr 2010 Director, Chairman, Bayer Yakuhin, Ltd. May 2014 Outside Director of the Company (current) Jun 2015 Outside Director, Towa Pharmaceutical Co., Ltd. (current) Apr 2016 Outside Director, Solasia Pharma K.K. (current) Jan 2017 Outside Director, FanPep Inc. (current) Jun 2018 Outside Director, Genetechnology Science Inc. (current Kidswell Bio Inc.) Aug 2023 Outside Director, AwakApp Inc. (current)

Apr 1974 Joined Sumitomo Chemical Company, Limited Aug 1999 General Manager, General Planning Office, Sumitomo Pharmaceuticals Co., Ltd.; General Manager, Pharmaceutical Business Office, Sumitomo Chemical Company, Limited Apr 2003 General Manager, Petrochemical Business Office, Sumitomo Chemical Company, Limited Jun 2005 Executive Officer, General Manager, Accounting Office, Sumitomo Chemical Company, Limited Apr 2008 Managing Executive Officer, Sumitomo Chemical Company, Limited Apr 2010 Senior Managing Executive Officer, Sumitomo Chemical Company, Limited Sep 2010 Managing Executive Officer, Dainippon Sumitomo Pharma Co., Ltd. (current Sumitomo Pharma Co., Ltd.) Jun 2011 Director, Managing Executive Officer, Dainippon Sumitomo Pharma Co., Ltd. Apr 2012 Director, Senior Managing Executive Officer, Dainippon Sumitomo Pharma Co., Ltd. Jun 2016 Advisor, Dainippon Sumitomo Pharma Co., Ltd. Mar 2018 Outside Director of the Company (current) Mar 2024 Outside Director, FanPep Inc. (current)

Apr 1999 Research Assistant, Tokushima University Dec 2001 Assistant Professor, Okayama University Jan 2005 Associate Professor, Tokyo University of Agriculture and Technology Apr 2005 Visiting Researcher, The University of Tokyo Apr 2011 Associate Professor, Keio University Aug 2013 Director, CTO, Dentsu Science Jam Inc. (current) Apr 2018 Professor, Faculty of Science and Technology and Faculty of Medicine, Keio University (current) Oct 2023 Representative Director, President, FeMup (current) Oct 2023 Representative Director, President, IKI Inc. (current) Nov 2024 Representative Director, President, IKI Japan (current) Jan 2025 Allround Co., Ltd. (current) Mar 2025 Outside Director of the Company (current) Apr 2025 Representative Director, President, MITS Technologies (current) May 2025 Director, CTO, 8illion Inc. (current) Oct 2025 Specially Appointed Professor, Tumor Research Center, Fujita Health University (current)

Apr 1979 Joined Ministry of Finance; assigned to Budget Bureau Jul 1985 Associate, Salomon Brothers Inc (New York) Sep 1988 Vice President, Shearson Lehman Hutton Securities Co. Sep 1989 Vice President, Shearson Lehman Hutton Inc. (New York) Sep 1991 Assistant Director, Barclays de Zoete Wedd (London) Jan 1993 Director, Barclays Securities Japan Limited Jun 1997 Senior Representative in Japan, CAL FP Bank Jul 1998 General Manager, Recof Co., Ltd. Feb 2001 Director, BNP Paribas Securities (Japan) Limited Oct 2006 Director, KPMG FAS Co., Ltd. Sep 2012 Managing Director, KPMG FAS Co., Ltd. Jul 2018 Managing Director, Lincoln International Inc. Jan 2023 Representative, Mori Associates (current) Mar 2025 Full-time Outside Audit & Supervisory Board Member of the Company (current)

Apr 1979 Joined Nomura Securities Co., Ltd. Dec 1997 General Manager, Toyama Branch, Nomura Securities Co., Ltd. Jun 2000 General Manager, Corporate Development Department, Nomura Securities Co., Ltd. Apr 2002 General Manager, Corporate Finance Department, Nomura Securities Co., Ltd. Apr 2009 Seconded as Director, Nomura Investor Relations Co., Ltd. Apr 2012 Managing Director, Nomura Investor Relations Co., Ltd. Apr 2015 Seconded to Pronexus Inc. as General Manager, Sales Development Department Dec 2016 Transferred to Pronexus Inc. Apr 2018 Executive Officer, Pronexus Inc. Apr 2020 Managing Executive Officer, General Manager, Solutions Business Division, Pronexus Inc. Jun 2021 Director, Managing Executive Officer, General Manager, Solutions Business Division, Pronexus Inc. Jul 2023 Joined SBI Holdings, Inc.; Director, seconded to SBI Alapromo Co., Ltd. Jun 2024 Part-time Audit & Supervisory Board Member, SBI Leasing Services Ltd. (current) Mar 2025 Outside Audit & Supervisory Board Member of the Company (current)

Apr 1984 Joined Ajinomoto Co., Inc. Apr 1997 Group Leader, Accounting and Finance Group, General Affairs Department, Ajinomoto Frozen Foods Co., Ltd. Jul 2002 Director in charge of Finance, Thai Ajinomoto Co., Ltd. Jul 2008 Senior Manager, Corporate Planning Department, Ajinomoto Co., Inc. Dec 2011 General Manager, Finance Department, Ajinomoto Pharma Co., Ltd. (current EA Pharma Co., Ltd.) Jul 2013 General Manager, Corporate Planning Department, Ajinomoto Pharma Co., Ltd. Jul 2016 General Manager, Corporate Planning Department, J-Oil Mills, Inc. Sep 2017 Senior Manager, Audit & Supervisory Office, Ajinomoto Co., Inc. Jul 2021 Staff, Audit Committee Support Group, Audit Department, Ajinomoto Co., Inc. (current) Mar 2025 Outside Audit & Supervisory Board Member of the Company (current)