Apr 1999 Joined Nihon Organon K.K.; Head of Pharmaceutical Research Laboratory Apr 2003 Representative Director, President of the Company (current) Mar 2011 President & CEO, CarnaBio USA, Inc. Dec 2011 General Manager, Sales Department of the Company Oct 2013 Representative Director, President, ProbeX Inc. Mar 2015 General Manager, Corporate Management Division of the Company Dec 2018 Outside Director, Medinet Co., Ltd. (current) Dec 2018 Outside Director, Kringle Pharma Inc. (current)

Sep 2001 Joined Dainippon Pharmaceutical Co., Ltd. (now Sumitomo Pharma Co., Ltd.) Jan 2007 Joined the Company May 2007 General Manager, Chemistry Research Department, Research and Technology Division of the Company Apr 2010 General Manager, Drug Discovery Research Department of the Company Mar 2015 Director, General Manager, Research and Development Division of the Company Apr 2023 Director, Chief Scientific Officer of the Company (current)

Nov 1995 Joined CSK Venture Capital Co., Ltd. Jan 2004 Joined the Company Mar 2004 Registered as Certified Public Accountant Jun 2009 General Manager, Accounting Department, Corporate Management Division of the Company Mar 2015 General Manager, Accounting and General Affairs Departments, Corporate Management Division of the Company Sep 2015 Deputy General Manager, Corporate Management Division; General Manager, Accounting Department of the Company Mar 2016 Director, Deputy General Manager, Corporate Management Division; General Manager, Accounting Department of the Company Mar 2017 Director, General Manager, Corporate Management Division; General Manager, Accounting Department of the Company Oct 2018 Director, General Manager, Corporate Management Division; General Manager, Accounting Department and Human Resources and General Affairs Department of the Company (current) Feb 2019 President, CarnaBio USA, Inc. (current)

Apr 1988 Joined Shionogi & Co., Ltd. Sep 2003 General Manager, Biology Division, Drug Discovery Research Laboratories, Shionogi & Co., Ltd. Apr 2005 General Manager, Frontier Drug Discovery Division, Drug Discovery Research Laboratories, Shionogi & Co., Ltd. Apr 2007 General Manager, Drug Development Department, Pharmaceutical Development Division, Shionogi & Co., Ltd. Apr 2011 General Manager, Global Project Management Department, Pharmaceutical Development Division, Shionogi & Co., Ltd. Jul 2018 General Manager, Clinical Development Department, Research and Development Division of the Company Feb 2019 Chief Development Officer, CarnaBio USA, Inc. (current) Mar 2023 Director, General Manager, Clinical Development Department, Research and Development Division of the Company Apr 2023 Director, Chief Development Officer of the Company (current)

Apr 1994 Joined Takeda Pharmaceutical Company Limited, Patent Department Mar 2003 Registered as Patent Attorney Oct 2006 Chief Member, Intellectual Property Department, Takeda Pharmaceutical Company Limited Apr 2007 Seconded to Takeda San Diego Inc. as Chief Member Feb 2009 Seconded to Takeda Pharmaceuticals North America as Chief Member Apr 2012 Head, IP TA CVM (Cardiovascular and Metabolic Diseases), Intellectual Property Department, Takeda Pharmaceutical Company Limited Apr 2018 Head, IP TA RM (Regenerative Medicine), Intellectual Property Department, Takeda Pharmaceutical Company Limited Apr 2020 Deputy General Manager, Intellectual Property Department, Nippon Shinyaku Co., Ltd. Apr 2021 General Manager, Intellectual Property Department, Nippon Shinyaku Co., Ltd. Jan 2025 General Manager, Intellectual Property and Legal Affairs Department of the Company Mar 2026 Director, General Manager, Intellectual Property and Legal Affairs Department of the Company (current)

Apr 1966 Joined Kanebo, Ltd. Jul 1996 General Manager, Business Planning Office, Kanebo, Ltd. Jul 2000 Managing Director, Kanebo Welfare Pension Fund Mar 2004 Corporate Auditor of the Company Mar 2020 Outside Director (Audit and Supervisory Committee Member) of the Company (current)

Oct 1982 Joined Asahi Accounting Corporation (now Azsa LLC) Jul 2010 Partner, Azsa LLC Sep 2014 Auditor, Azsa LLC Apr 2018 Specially Appointed Professor, Graduate School of Accountancy, Kansai University Mar 2019 Corporate Auditor of the Company Mar 2020 Outside Director (Audit and Supervisory Committee Member) of the Company (current) Apr 2020 Part-time Lecturer, Kansai University and its Graduate School of Accountancy (current) Jun 2020 Outside Director, Air Water Inc. (current)

Apr 1983 Joined Daiichi Pharmaceutical Co., Ltd., Research Planning Department Apr 1992 Official, International Development Department, Daiichi Pharmaceutical Co., Ltd. Apr 1996 Seconded to Daiichi Pharmaceutical (China) Co., Ltd. as Head of Development Department Apr 1999 Section Manager, Research Planning and Promotion Department, Daiichi Pharmaceutical Co., Ltd. Apr 2000 Deputy Manager, Business Development and Licensing Department, Daiichi Pharmaceutical Co., Ltd. Oct 2005 Business Development Director, Roche Partnering / Roche Pharma Japan Apr 2010 Representative; Japan/Korea Business Development Head, Roche Partnering / Roche Pharma Japan Mar 2022 Senior Advisor, Roche Partnering / Roche Pharma Japan (current) Mar 2024 Outside Director of the Company Mar 2026 Outside Director (Audit and Supervisory Committee Member) of the Company (current)

Oct 1977 Joined Tohmatsu & Aoki Audit Corporation (now Deloitte Touche Tohmatsu LLC) Jun 1981 Registered as Certified Public Accountant Jun 1998 Partner, Tohmatsu Audit Corporation (now Deloitte Touche Tohmatsu LLC) Jun 2005 Representative Partner, Tohmatsu Audit Corporation (now Deloitte Touche Tohmatsu LLC) Jul 2017 Managing Director, JSH Co., Ltd. Apr 2018 Representative Director and Managing Director, JSH Co., Ltd. Jul 2025 Opened Terada Certified Public Accountant Office (current) Mar 2026 Outside Director (Audit and Supervisory Committee Member) of the Company (current)