Apr 1987 Joined Otsuka Pharmaceutical Factory, Inc. (OPF) Jun 1997 Director, Consumer Products Development Division Manager, Otsuka Pharmaceutical Co., Ltd. Jun 1998 Managing Director, in charge of Consumer Products, Promotion, Sales Promotion and Development, Otsuka Pharmaceutical Co., Ltd. Dec 2001 Director, in charge of R&D, OPF May 2002 Representative Director, OPF Dec 2003 Representative Director, Executive Vice President, OPF Dec 2004 Representative Director, President, OPF Jul 2008 Director, the Company Jun 2010 Director, Executive Vice President, the Company Jun 2014 Representative Director, OPF; Representative Director, Vice Chairman, the Company Mar 2015 Director, Otsuka Pharmaceutical Co., Ltd. (current) Chairman and Director, OPF Representative Director, Chairman, the Company (current) Mar 2022 Representative Director, OPF (current)

Apr 1983 Joined Otsuka Pharmaceutical Co., Ltd. Jun 2008 Executive Officer, Diagnostics Business Division Head, Otsuka Pharmaceutical Co., Ltd. Jun 2009 Managing Executive Officer, Deputy Head, Pharmaceutical Business Division, Otsuka Pharmaceutical Co., Ltd. Mar 2015 Director and Senior Managing Executive Officer, Head of Nutraceuticals Business Division, Otsuka Pharmaceutical Co., Ltd. Apr 2015 Director, Pharmabite LLC Mar 2017 Managing Director, in charge of Nutraceuticals Business, Otsuka Pharmaceutical Co., Ltd. Sep 2017 Director, Dayafoods Inc. Mar 2018 Senior Managing Director, in charge of Nutraceuticals Business, Otsuka Pharmaceutical Co., Ltd. Oct 2018 Chairman, Director, Nardobel SAS Mar 2019 Vice President, Director, Otsuka Pharmaceutical Co., Ltd. Mar 2020 Representative Director, President, Otsuka Pharmaceutical Co., Ltd. (current) Director, the Company Jan 2024 Representative Director, COO, the Company Jan 2025 Representative Director, President and CEO, the Company (current)

Apr 1985 Joined Otsuka Pharmaceutical Co., Ltd. Jan 2003 Assistant General Manager, General Affairs Department, Executive Officer, Otsuka Pharmaceutical Co., Ltd. Jun 2006 General Manager, General Affairs Department, Executive Officer, Otsuka Pharmaceutical Co., Ltd. Nov 2007 General Manager, General Affairs Department, in charge of Legal, Planning and External Affairs, Managing Executive Officer, Otsuka Pharmaceutical Co., Ltd. Jul 2008 Managing Director, in charge of General Affairs, the Company Mar 2016 Senior Managing Director, in charge of General Affairs, the Company Jan 2017 Director, Otsuka Medical Devices Co., Ltd. Mar 2022 Representative Director, Vice President, Otsuka Pharmaceutical Co., Ltd. (current) Vice President, Director, the Company Mar 2023 Director, Otsuka Foods Co., Ltd. Jan 2025 Representative Director, Vice President, the Company (current)

Apr 1982 Joined Otsuka Pharmaceutical Co., Ltd. Apr 1993 Joined Deloitte & Touche LLC, Seattle Office (now Deloitte Touche Tohmatsu LLC) Apr 1996 Joined Baxter K.K. Apr 2000 Joined Otsuka Pharmaceutical Co., Ltd. Mar 2015 General Manager, Corporate Finance and Accounting Department, the Company Sep 2016 Executive Officer, General Manager, Corporate Finance and Accounting Department, the Company; Executive Officer, General Manager, Accounting Department, Otsuka Pharmaceutical Co., Ltd. Apr 2017 Executive Officer, General Manager, Tax Department, the Company; Executive Officer, General Manager, Financial Accounting Department, Otsuka Pharmaceutical Co., Ltd. Mar 2018 Director, in charge of Finance, the Company Mar 2019 Director, CFO, the Company (current) Mar 2022 Director, in charge of Finance, Otsuka Pharmaceutical Co., Ltd.

Apr 1989 Joined Tobishima Corporation Sep 1995 Joined Otsuka Pharmaceutical Co., Ltd. Aug 2002 Finance Department, OIAA Business Division, Otsuka Pharmaceutical Co., Ltd. Jul 2003 Accounting Department, Otsuka Pharmaceutical Co., Ltd. Mar 2015 Executive Officer, in charge of India, OPF May 2015 CEO, Claris Otsuka Pvt. Ltd. (now Otsuka Pharmaceutical India Pvt. Ltd.) Jan 2019 Managing Executive Officer, in charge of Corporate Strategy Office, the Company Mar 2019 Director, in charge of Finance and Business Portfolio Management, Otsuka Pharmaceutical Co., Ltd.; Director, in charge of Business Portfolio Management, the Company Oct 2021 President and Director, Otsuka America, Inc. Mar 2022 Managing Director, in charge of Business Strategy and Otsuka America, Inc., Otsuka Pharmaceutical Co., Ltd.; Managing Director, CSO, the Company Feb 2023 Chairman and Director, Otsuka America, Inc. Mar 2023 Director, OPF Jan 2024 Director, the Company (current) Representative Director, President, OPF (current)

Apr 1989 Joined Daiwa Bank, Ltd. (now Resona Bank, Ltd.) Oct 1993 Joined Taiho Pharmaceutical Co., Ltd. Aug 2002 President and Director, Taiho Pharma U.S.A., Inc. (now Taiho Oncology, Inc.) Sep 2003 Director, Taiho Pharmaceutical Co., Ltd. Apr 2010 President and CEO, Director, Otsuka America, Inc. Apr 2012 Representative Director, President, Taiho Pharmaceutical Co., Ltd. (current); Director, Taiho Pharma U.S.A., Inc. Apr 2014 Chairman and Director, Taiho Oncology, Inc. (current) Mar 2017 Director, the Company (current)

Apr 1987 Joined Goldman Sachs Securities Co., Ltd. Aug 1991 Joined Shearson Lehman Brothers Jul 2002 Engagement Manager, McKinsey & Company, Japan Office Jun 2006 Director, Intel Capital Japan, Intel K.K. Aug 2008 Managing Director, in charge of Corporate Planning, the Company Feb 2011 Director, Otsuka Medical Devices Co., Ltd. Apr 2012 President and CEO, Director, Otsuka America, Inc. Aug 2015 CEO, Director, Pharmabite LLC Jan 2017 Representative Director, President, Otsuka Medical Devices Co., Ltd. (current) May 2017 Director, Otsuka America, Inc. Aug 2017 Chairman, Director, Pharmabite LLC Mar 2018 Director, the Company (current)

Mar 1977 Joined Otsuka Pharmaceutical Co., Ltd. Jun 1998 Senior Managing Director, in charge of Pharmabite, Otsuka Pharmaceutical Co., Ltd. Nov 1998 Vice President and Director, Otsuka Pharmaceutical Co., Ltd. Jun 1999 Director, in charge of U.S. Business, Otsuka Pharmaceutical Co., Ltd. Jun 2000 Representative Director, President, Otsuka Pharmaceutical Co., Ltd. Jun 2008 Director, Otsuka Pharmaceutical Co., Ltd. Jul 2008 Representative Director, President and CEO, the Company Dec 2011 Director, Otsuka Chemical Co., Ltd. Feb 2015 Representative Director, President, Otsuka Pharmaceutical Co., Ltd. Mar 2020 Representative Director, Chairman, Otsuka Pharmaceutical Co., Ltd. Jan 2025 Director, Senior Advisor, the Company (current) Chairman and Director, Otsuka Pharmaceutical Co., Ltd. (current)

Apr 1975 Resident Physician, Pediatrics, St. Luke's International Hospital Oct 1981 Joined Ministry of Health and Welfare (now Ministry of Health, Labour and Welfare) Aug 2005 Director-General, Medical Affairs Bureau, Ministry of Health, Labour and Welfare Aug 2007 Director, Tama Zenshoen National Sanatorium Apr 2012 Director-General, National Institute of Public Health Dec 2015 Vice President, International University of Health and Welfare Mar 2016 Outside Director, the Company (current) Jun 2019 Chairman, Japan Public Health Association Jun 2025 Chairman, Japan Public Health Association (current)

Apr 1974 Joined Itochu Corporation Jun 2003 Executive Officer, Itochu Corporation Apr 2009 Managing Executive Officer, President, Food Company, Itochu Corporation Apr 2010 Representative Director, Senior Managing Executive Officer, President, Food Company, Itochu Corporation Mar 2017 Executive Advisor, Itochu Corporation (current) Jun 2017 Outside Director, Arata Corporation Mar 2019 Outside Director, the Company (current)

Apr 1983 Joined Morgan Stanley MUFG Securities Co., Ltd. (formerly Morgan Stanley Securities Co., Ltd.) Jan 1989 Equity Research Department (Healthcare), Morgan Stanley Securities Co., Ltd. Dec 2000 Managing Director, Morgan Stanley Securities Co., Ltd. Dec 2013 Senior Advisor, Healthcare, Investment Banking Division, Morgan Stanley MUFG Securities Co., Ltd. Mar 2020 Outside Director, the Company (current) Jun 2023 Outside Audit & Supervisory Board Member, Mitsui Fudosan Co., Ltd. (current)

Oct 1985 Joined Sanwa Tokyo Marunouchi Office (now Deloitte Touche Tohmatsu LLC) Apr 1989 Registered as Certified Public Accountant Jul 1996 Partner, Tohmatsu & Co. (now Deloitte Touche Tohmatsu LLC) Apr 2010 Member, Public Interest Certification Committee, Cabinet Office Oct 2012 Director, Advisory Development Department, Deloitte Touche Tohmatsu LLC Nov 2013 Board Member, Deloitte Touche Tohmatsu LLC Jun 2017 Head of Industry Business Division, Advisory Business Headquarters, Deloitte Touche Tohmatsu LLC Jun 2019 Thought Leader, Deloitte Tohmatsu LLC Sep 2021 Advisor, Kanagawa Prefectural Government (current) Mar 2022 Outside Director, the Company (current)

Apr 1986 Joined Tokyo Bank, Ltd. (now MUFG Bank, Ltd.) Mar 1999 Joined Merrill Lynch Japan Securities Co., Ltd. Jul 2010 Representative Director, President, Merrill Lynch Japan Securities Co., Ltd.; Japan Country Head, Bank of America Corporation (BofA) Oct 2013 Head of Asia Pacific, BofA Global Corporate & Investment Banking Jun 2016 Representative Director, President, Merrill Lynch Japan Securities Co., Ltd.; Japan Country Head, BofA Jan 2019 Co-President of APAC, BofA Jul 2023 Senior Advisor, Asia Pacific, BofA Mar 2025 Outside Director, the Company (current) Jun 2025 Outside Director, Resona Holdings, Inc. (current)

Apr 1979 Joined Otsuka Chemical Co., Ltd. Jan 1995 General Manager, Information Center, Otsuka Chemical Co., Ltd. Jan 2006 CFO, Trocelen GmbH May 2009 Executive Officer, General Manager, Information Systems Department, Otsuka Chemical Holdings Co., Ltd. (now Otsuka Chemical Co., Ltd.) Jun 2009 Executive Officer, IT Division Manager, Corporate Finance and Accounting Department, the Company Dec 2011 Director, in charge of General Affairs, Accounting and IT, Otsuka Chemical Co., Ltd. Mar 2015 Managing Executive Officer, Corporate Finance and Accounting Department (concurrently Corporate Services Department), the Company Mar 2018 Full-time Audit & Supervisory Board Member, the Company (current) Mar 2019 Audit & Supervisory Board Member, Otsuka Chemical Co., Ltd. (current)

Oct 1997 Joined Chuo Audit Corporation Oct 2000 Joined Tohmatsu & Co. (now Deloitte Touche Tohmatsu LLC) Apr 2002 Registered as Certified Public Accountant Feb 2006 Vice President, Will Capital Management Co., Ltd. Jun 2010 Outside Audit & Supervisory Board Member, the Company (current) Jun 2012 Outside Audit & Supervisory Board Member, Otsuka Pharmaceutical Co., Ltd. Oct 2013 Outside Director, Nihon Parking Development Co., Ltd. Mar 2016 Audit & Supervisory Board Member, Otsuka Pharmaceutical Co., Ltd. (current) Aug 2018 Outside Director, Inbound Platform Inc. (current)

Apr 1998 Registered as Attorney-at-law (Dai-Ichi Tokyo Bar Association); joined Kajitani Sogo Law Offices (current) Oct 2005 Admitted to the New York State Bar Jun 2015 Outside Director (Audit and Supervisory Committee Member), Lintec Corporation (current) Apr 2021 Member, Subcommittee on Secured Transactions, Legislative Council of the Ministry of Justice May 2021 Director, Turnaround Management Association Jun 2021 Outside Director, TPR Co., Ltd. (current) Mar 2022 Outside Audit & Supervisory Board Member, the Company (current) Jun 2022 Outside Audit & Supervisory Board Member, Toshiba Tec Corporation (current) May 2023 Managing Director, Turnaround Management Association (current)

Oct 1996 Joined Tohmatsu & Co. (now Deloitte Touche Tohmatsu LLC) Apr 1999 Registered as Certified Public Accountant Jul 2015 Representative Director, S-Plus Inc. (now Bizsupply Inc.) (current) Jun 2016 Director, Japan Association of Certified Fraud Examiners (current) Mar 2021 Outside Director (Audit and Supervisory Committee Member), SBS Holdings, Inc. (current) Jun 2021 Outside Audit & Supervisory Board Member, Shindengen Electric Manufacturing Co., Ltd. Mar 2022 Outside Audit & Supervisory Board Member, the Company (current)