Apr 1983 Joined Ono Pharmaceutical Co., Ltd.; assigned to Clinical Development Department Aug 1994 Joined Japan Tobacco Inc.; assigned to Pharmaceutical Research Institute Apr 1999 Appointed Head of Research Planning Department Mar 2002 Appointed Head of R&D Planning Department Aug 2003 Appointed Senior Investigator, Pharmaceuticals Business Division Mar 2004 Established the Company; appointed Representative Director, President, in charge of R&D Nov 2009 Appointed Member, Bio Innovation Study Group (Ministry of Economy, Trade and Industry) Aug 2016 Appointed CEO and Chairman of the Board, Oncolys USA Inc. (current) Apr 2020 Appointed CEO and Chairman of the Board, OPA Therapeutics Inc. (current) Jan 2021 Appointed Representative Director, President, in charge of R&D and Business Development Jun 2023 Appointed Representative Director, President, in charge of R&D and CMC Dec 2025 Appointed Representative Director, President (current)

Apr 1991 Joined Nippon Ciba-Geigy K.K. Jan 1997 Joined Santen Pharmaceutical Co., Ltd. Aug 2002 Studied at Trinity College Dublin; obtained MBA Apr 2003 Rejoined Santen Pharmaceutical Co., Ltd.; appointed Manager, Licensing Department Feb 2005 Joined UMN Pharma Inc.; appointed Representative Director, President Dec 2007 Joined the Company Mar 2008 Appointed Director, in charge of Business Development Aug 2016 Appointed President, Oncolys USA Inc. Sep 2016 Appointed Director, Liquid Biotech USA, Inc. Apr 2017 Appointed Director, Precision Virologics Inc. Nov 2017 Appointed President, Liquid Biotech USA, Inc. Feb 2018 Appointed Director, Unleash Immuno Oncolytics, Inc. Jan 2020 Appointed Director, Oncolys USA Inc. (current) Apr 2020 Appointed Director, OPA Therapeutics Inc. (current) Aug 2022 Appointed Director, in charge of CMC Planning and Overseas Relations Jun 2023 Appointed Director, in charge of Business Development Mar 2024 Appointed Director, in charge of Business Development and Risk Management Apr 2024 Appointed Managing Director, in charge of Business Development and Risk Management (current)

Apr 1987 Joined House Foods Corporation; assigned to Finance Department Feb 1993 Joined Kirin Brewery Company, Limited; assigned to Accounting Department Apr 1996 Assigned to Planning Department, Pharmaceutical Business Division Apr 2000 Assigned to Accounting Department Apr 2005 Appointed General Manager, Corporate Planning Department, Kirin Beverage Company, Limited Apr 2009 Appointed General Manager, Accounting Department, Kirin Kyowa Foods Co., Ltd. Apr 2012 Appointed Senior Manager, Research Department, Kirin Holdings Company, Limited Apr 2014 Appointed General Manager, Accounting Support Department, Kirin Business Expert Co., Ltd. Apr 2020 Appointed Full-time Audit & Supervisory Board Member, Kyowa Hakko Bio Co., Ltd. (current) Mar 2026 Appointed Director of the Company (current)

Apr 1980 Joined Japan Monopoly Corporation (now Japan Tobacco Inc.) Jun 2005 Appointed Director, Applied Biosystems Japan Ltd. (now Life Technologies Japan Ltd.) Oct 2009 Appointed Representative Director, President, New England Biolabs Japan, Inc. Oct 2011 Appointed Senior Managing Executive Officer, CSI Japan Co., Ltd. Oct 2015 Appointed Executive Officer and Chief Financial Officer, Kendepot Co., Ltd. Apr 2018 Appointed Representative Director, President, Kendepot Co., Ltd. Mar 2020 Appointed Director and Executive Officer in charge of Business Development, GNI Group Ltd. Aug 2021 Appointed Outside Director, Dynamics Co., Ltd. Mar 2022 Appointed Outside Director of the Company (current) Aug 2022 Appointed Representative Director, President, Dynamics Co., Ltd. Jul 2024 Appointed Representative Director, Yukoyuko Holdings Co., Ltd. (current) Apr 2025 Appointed Representative Director, UC AnimalCare Partners Co., Ltd. (current) Jun 2025 Appointed Outside Director, Igualfan Co., Ltd. (current)

Apr 1984 Joined Pharmacy Department, Jichi Medical University Hospital Jul 2000 Joined Medical Planet Co., Ltd.; appointed Vice President and Director Mar 2005 Appointed Representative Director, President, Medical Creation Co., Ltd. Feb 2007 Appointed Representative Director, President, Medical Information Research Institute Co., Ltd. Jul 2009 Joined Tera Co., Ltd.; assigned to Business Development Office; appointed Head of Business Development Office Mar 2010 Appointed Director, Tera Co., Ltd. Jun 2014 Joined Tokyo University of Science as Staff; assigned to Office of the President; appointed Assistant to Executive Director Mar 2016 Appointed Outside Director, Symbio Pharmaceuticals Co., Ltd. Aug 2017 Appointed Representative Director, President, Qualips Co., Ltd. Jan 2020 Joined McDonald's Co. (Japan), Ltd.; appointed Director, CSR, Communications & Corporate Relations Division Dec 2022 Appointed Director, Corporate Relations, Communications & Corporate Relations Division Mar 2023 Appointed Outside Director of the Company (current) Apr 2023 Appointed Executive Fellow, Assistant to the President, Kyoto Prefectural University of Medicine Apr 2024 Appointed Assistant to the President and Specially Appointed Professor, Kyoto Prefectural University of Medicine (current)

Apr 1978 Joined Information Service Bureau Co., Ltd. (now I.S.B. Co., Ltd.) Jan 2002 Appointed Executive Officer and General Manager, Field Solutions Business Division, I.S.B. Co., Ltd. Jan 2009 Appointed General Manager, Internal Control Promotion Department, I.S.B. Co., Ltd. Jan 2016 Appointed General Manager, Audit Office, I.S.B. Co., Ltd. Mar 2020 Appointed Director and Full-time Audit and Supervisory Committee Member, I.S.B. Co., Ltd. Apr 2024 Appointed Advisor, I.S.B. Co., Ltd. Mar 2025 Appointed Full-time Audit & Supervisory Board Member of the Company (current)

Oct 2001 Registered as attorney-at-law (Dai-Ichi Tokyo Bar Association) Apr 2006 Appointed Contract Attorney, Public Relations and Research Office, Dai-Ichi Tokyo Bar Association Apr 2010 Appointed Civil Conciliation Commissioner, Musashino Summary Court (current) Feb 2015 Appointed Director, Research Office, Japan Federation of Bar Associations Apr 2016 Appointed Special Contract Attorney to the Secretary General, Japan Federation of Bar Associations Apr 2017 Appointed Managing Director, Tokyo Civil Conciliation Association Federation; Secretary General, Musashino Civil Conciliation Association May 2018 Joined Oku, Katayama & Sato Law Office as Partner (current) Apr 2020 Appointed Vice President, Dai-Ichi Tokyo Bar Association Mar 2021 Appointed Substitute Audit & Supervisory Board Member of the Company Jan 2022 Appointed Judicial Commissioner, Musashino Summary Court (current) Mar 2025 Appointed Outside Audit & Supervisory Board Member of the Company (current)

Oct 1990 Joined Ota Showa Audit Corporation (now EY ShinNihon LLC) Apr 1996 Registered as Certified Public Accountant Apr 1996 Opened Nagasue Certified Public Accountant Office (current) May 2018 Appointed Full-time Audit & Supervisory Board Member, Samantha Thavasa Japan Limited Dec 2023 Appointed Outside Audit & Supervisory Board Member, Spread Co., Ltd. Mar 2024 Appointed Substitute Audit & Supervisory Board Member of the Company Mar 2025 Appointed Outside Audit & Supervisory Board Member of the Company (current)